12. Consider the following reaction
CH3

Question

12. Consider the following reaction
CH3
H3C-C-CH2CH3
1
+
H2O
CH3
H3C-C-CH2CH3
OH2
+
1
What happens to the reaction rate in each of the following instances? (10 points)
i) The leaving group is changed from I to Cl-
ii) The solvent is changed from water to Acetone
iii) The alkyl halide is changed from (CH3)2C(1)CH2CH3 to (CH3)2CHCH(I)CH3-
iv) The concentration of water is increased by a factor of four
v) The concentrations of both the alkyl halide and water are increased by a factor of four.

Kunduz · Accepted Answer

CHO
CH3
Hao
H₂C-C-CH₂ CH 3
CH3 -C- CH2CH3 + I-
+ DH 2
the
The folloning reaction is perample of
Cocample of SN' reaction
Mate” have for sN' reaction
for Sa' reaction uusitten as
Rate = [CCH3)2 IC CH2 CH3]
Maclant,
That means date only depend upon.conen of
and Departure of leaving group
CH3
CH3
CH3 -C- CH2CH3
He
-CH₂CH3
C-C-
I
(
-TO
carbocationic intermediate
ů so when leaving group
changes from I to uo
10
the rate
of
reaction decreases becouse elo is not a
much governd' Leaving group as to

12. Consider the following reaction CH3 H3C-C-CH2CH3 1 + H2O CH3 H3C-C-CH2CH3 OH2 + 1 What happens to the reaction rate in each