Question:

Why can some patients develop toxic responses to drugs even when their plasma levels are in the therapeutic range? A. there is a higher level of the free fraction of the drug in the patient's plasma B

Why can some patients develop toxic responses to drugs even when their plasma levels are in the therapeutic range?
A. there is a higher level of the free fraction of the drug in the patient's plasma
B. there is a higher level of the bound fraction of the drug in the patient's plasma
C. drugs given before bed can become toxic
D. A toxic response can not occur if the drug is within the therapeutic range

Why can some patients develop toxic responses to drugs even when their plasma levels are in the therapeutic range? A. there is a higher level of the free fraction of the drug in the patient's plasma B. there is a higher level of the bound fraction of the drug in the patient's plasma C. drugs given before bed can become toxic D. A toxic response can not occur if the drug is within the therapeutic range